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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1489220Generated: October 25, 2026

Methyl alpha-cyclohexyl-alpha-hydroxybenzeneacetate → 4-[Ethyl-[(4-methoxyphenyl)methyl]amino]but-2-ynyl 2-cyclohexyl-2-hydroxy-2-phenylacetate

https://huagongshe.com/reaction/1489220

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl alpha-cyclohexyl-alpha-hydroxybenzeneacetateHCID 112035—
Reactant4-[Ethyl-[(4-methoxyphenyl)methyl]amino]but-2-yn-1-olHCID 4248190—
Product4-[Ethyl-[(4-methoxyphenyl)methyl]amino]but-2-ynyl 2-cyclohexyl-2-hydroxy-2-phenylacetateHCID 5044225—

Reaction Steps

reacting methyl α-cyclohexyl-α-hydroxybenzeneacetate with 4-[N-ethyl-(4-methoxyphenyl)methylamino]-2-butyn-1-ol in the presence of an anhydrous base to produce 4-[N-ethyl-(4-methoxyphenyl)methylamino]-2-butynyl α-cyclohexyl-α-hydroxybenzeneacetate; and

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05677346
Source datasetuspto-grants-1997_10
ORD IDord-f543ff470aa04c16993e843a28d3c825
Source noteuspto-grants-1997_10