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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1489221Generated: October 27, 2026

4-[Ethyl-[(4-methoxyphenyl)methyl]amino]but-2-ynyl 2-cyclohexyl-2-hydroxy-2-phenylacetate → N-Desethyloxybutynin

https://huagongshe.com/reaction/1489221

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[Ethyl-[(4-methoxyphenyl)methyl]amino]but-2-ynyl 2-cyclohexyl-2-hydroxy-2-phenylacetateHCID 5044225—
ReactantCarbonochloridateHCID 21226386—
SolventMethanolHCID 887—
ProductN-DesethyloxybutyninHCID 133577—

Reaction Steps

reacting said 4-[N-ethyl-(4-methoxyphenyl)methylamino]-2-butynyl α-cyclohexyl-α-hydroxybenzeneacetate sequentially with a carbonochloridate and methanol to produce 4-(ethylamino)-2-butynyl α-cyclohexyl-α-hydroxybenzeneacetate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05677346
Source datasetuspto-grants-1997_10
ORD IDord-2788e3e5f2d04f0fac845cf0cb3fdb1e
Source noteuspto-grants-1997_10