Potassium Hydroxide → HCID 53758222, compound

HRID 1489225Notes

Reaction equation

HRID 1489225 reaction equation
[CH3:1][O:2][N:3]=[C:4]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[CH2:13][O:14][C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([Cl:21])[CH:16]=1)[C:5]#[N:6].[OH-:22].[K+]>>[CH3:1][O:2][N:3]=[C:4]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[CH2:13][O:14][C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([Cl:21])[CH:16]=1)[C:5]([NH2:6])=[O:22]

Participants

3

Reactant 2

HCID 14797Potassium HydroxideHCID 54156575HCID 54156575, compound

Product 1

HCID 53758222HCID 53758222, compoundYield 58%

Conditions

Temperature
80 °C

Procedure

7.0 g (23 mmol) of 2-methoxyimino-2-[2-(m-chlorophenoxymethyl)-phenyl]acetonitrile were added to a mixture of 50 ml of glycol and 10 ml of a 25% by weight aqueous solution of potassium hydroxide, and the reaction mixture was then heated at 80° C. for 2 hours. The solid was then separated off, washed with methyl tert-butyl ether and dried. Yield: 58%;

Workup

  1. customThe solid was then separated off
  2. washwashed with methyl tert-butyl ether
  3. customdried

Sources & evidence

ORD record
ord-4f80c7e9a59044a4a064187ec3ad5608
Source dataset
uspto-grants-1997_10
Patent number
US05677347

Reaction notes

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