HuagongsheHuagongshe Chemistry Print Report · For research reference only
Putrescine → Spermidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Putrescine | HCID 1045 | — |
| Reactant | Spermidine | HCID 1102 | — |
| Product | Spermidine | HCID 1102 | — |
| Product | Spermine | HCID 1103 | — |
Reaction Steps
In vivo, the first step in the biosynthesis of spermidine and spermine is decarboxylation of ornithine (2,5-diaminopentanoic acid, H2 N(CH2)3CH(NH2)CO2H) by ornithine decarboxylase (ODC) to yield putrescine. Spermidine is then synthesized by transfer of an activated aminopropyl group from S-adenosyl S-methyl homocystaeamine to putrescine. Spermine is formed by addition of a further aminopropyl group to spermidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05677350 |
| Source dataset | uspto-grants-1997_10 |
| ORD ID | ord-3c01fb6e0959484584beed8233298ceb |
| Source note | uspto-grants-1997_10 |