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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1489280Generated: October 25, 2026

3,4-Diethoxybenzene-1-carbothioamide → 2-(3,4-Diethoxyphenyl)-4-(5-carboxy-2-pyrimidyl)thiazole

https://huagongshe.com/reaction/1489280

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-Diethoxybenzene-1-carbothioamideHCID 7745250—
Reactant5-Ethoxycarbonyl-2-(alpha-bromoacetyl)pyrimidineHCID 18707325—
Product2-(3,4-Diethoxyphenyl)-4-(5-carboxy-2-pyrimidyl)thiazoleHCID 18707372—

Reaction Steps

5-Ethoxycarbonyl-2-(α-bromoacetyl)pyrimidine and 3,4-diethoxythiobenzamide were subjected to the same reaction as in Example 1 and then to the same hydrolysis as in Example 147 to obtain 2-(3,4-diethoxyphenyl)-4-(5-carboxy-2-pyrimidyl)thiazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05677319
Source datasetuspto-grants-1997_10
ORD IDord-b5e2c9dca62844a59cc78a1b4620a298
Source noteuspto-grants-1997_10