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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1489281Generated: October 25, 2026

3,4-Diethoxybenzene-1-carbothioamide → 2-(3,4-Diethoxyphenyl)-4-(4-carboxy-2-pyrrolyl)thiazole

https://huagongshe.com/reaction/1489281

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-Diethoxybenzene-1-carbothioamideHCID 7745250—
Reactant4-Ethoxycarbonyl-2-(alpha-bromoacetyl)pyrroleHCID 18707121—
Product2-(3,4-Diethoxyphenyl)-4-(4-carboxy-2-pyrrolyl)thiazoleHCID 18707337—

Reaction Steps

4-Ethoxycarbonyl-2-(α-bromoacetyl)pyrrole and 3,4- diethoxythiobenzamide were subjected to the same reaction as in Example 1 and then to the same hydrolysis as in Example 147 to obtain 2-(3,4-diethoxyphenyl)-4-(4-carboxy-2-pyrrolyl)thiazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05677319
Source datasetuspto-grants-1997_10
ORD IDord-8906f8dfd6e44e248c3f7eef245f7878
Source noteuspto-grants-1997_10