Sodium Carbonate → HCID 21709154, compound

HRID 1489352Notes

Reaction equation

HRID 1489352 reaction equation
[C:1]1([C:7]2[CH:12]=[C:11]([CH3:13])[CH:10]=[CH:9][N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C(=O)([O-])[O-].[Na+].[Na+].[Br:20]Br>C(Cl)(Cl)(Cl)Cl>[C:1]1([C:7]2[CH:12]=[C:11]([CH2:13][Br:20])[CH:10]=[CH:9][N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 10340Sodium CarbonateHCID 24408BromineHCID 770264-Methyl-2-phenylpyridine

Product 1

HCID 21709154HCID 21709154, compound

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

To a solution of 100 mg of 2-phenyl-4-methylpyridine in 2 mL of carbon tetrachloride was added 300 mg of sodium carbonate and 100 mg of bromine. The reaction mixture was stirred and irradiated with a 500 W lamp for 1 h, filtered and the solvent removed by evaporation under reduced pressure to yield 2-phenyl-4-bromomethylpyridine which was used in the next step without further purification or characterization.

Workup

  1. customirradiated with a 500 W lamp for 1 h
  2. filtrationfiltered
  3. customthe solvent removed by evaporation under reduced pressure

Sources & evidence

ORD record
ord-10a08aec74934b09879e31f70a70fc26
Source dataset
uspto-grants-1997_10
Patent number
US05677454

Reaction notes

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