HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → Diethyl 3-(tert-Butyldimethylsilyloxy)glutarate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | tert-Butyldimethylsilyl chloride | HCID 28928 | — |
| Reactant | Diethyl 3-hydroxyglutarate | HCID 96259 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Diethyl 3-(tert-Butyldimethylsilyloxy)glutarate | HCID 13327289 | — |
Reaction Steps
Imidazole and tert-butylchlorodimethylsilane are added to a solution of diethyl 3-hydroxyglutarate in methylene chloride, and the reaction is performed to give diethyl 3-[(tert-butydimethylsilyl)oxy]pentanedioate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05677455 |
| Source dataset | uspto-grants-1997_10 |
| ORD ID | ord-e4ee71123c4e460d8e6cc9a2a88f101a |
| Source note | uspto-grants-1997_10 |