Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | (L)-ethyl lactate | HCID 92831 | — |
| Product | HCID 11062669 | HCID 11062669 | 68.7% |
Reaction Steps
A mixture of 75 g of (S)-ethyl lactate and 164 g of morpholine was heated at 80° C. for 64 hours. The reaction solution was concentrated and purified by silica gel chromatography (eluent; hexane:ethyl acetate=4:1 to ethyl acetate) to give 69.4 g of 4-[(S)-2-hydroxypropionyl]morpholine as a pale yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05677464 |
|---|
| Source dataset | uspto-grants-1997_10 |
|---|
| ORD ID | ord-95031e7cfbeb4d218c5cdad1654d3006 |
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| Source note | uspto-grants-1997_10 |
|---|
