HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Toluenesulfonyl chloride → N-Benzyl-3,4-dimethoxyamphetamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Toluenesulfonyl chloride | HCID 7397 | — |
| Reactant | Benzylamine | HCID 7504 | — |
| Reactant | 3,4-Dimethoxy-alpha-methylbenzeneethanol | HCID 89187 | — |
| Product | N-Benzyl-3,4-dimethoxyamphetamine | HCID 410200 | — |
Reaction Steps
The 1-(3,4-dimethoxyphenyl)-2-propanol obtained above was subjected to sulfonylation by p-toluenesulfonyl chloride and reacted with benzylamine to give N-benzyl-3,4-dimethoxyamphetamine. The resultant compound was converted into 3,4-dimethoxyamphetamine by hydrogenation decomposition under hydrogen atmosphere with 5% Pd-C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05679557 |
| Source dataset | uspto-grants-1997_10 |
| ORD ID | ord-23230580570741439b6da90e8ab163d9 |
| Source note | uspto-grants-1997_10 |