Dimethylamine → Isododecyldimethylamine

HRID 1489497Notes

Reaction equation

HRID 1489497 reaction equation
[CH2:1](Cl)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH:10]([CH3:12])[CH3:11].[CH3:14][NH:15][CH3:16].[OH-].[Na+]>>[CH2:1]([N:15]([CH3:16])[CH3:14])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH:10]([CH3:12])[CH3:11]

Participants

4

Reactant 3

HCID 674DimethylamineHCID 14798Sodium HydroxideHCID 22901855Isododecyl chloride

Product 1

HCID 18676636IsododecyldimethylamineYield 98.1%

Procedure

In a 1-gallon stainless steel autoclave was charged 4.5 moles of isododecyl chloride, 13.5 moles of dimethylamine (as 40% aqueous solution), and 4.5 moles of sodium hydroxide (as 50% aqueous solution). The mixture was heated at 175°-190° C. for 6 hours. The mixture was cooled. The top organic layer was collected and the residual dimethylamine evaporated. The isododecyldimethylamine was obtained in 98.1% yield.

Workup

  1. temperatureThe mixture was heated at 175°-190° C. for 6 hours
  2. temperatureThe mixture was cooled
  3. customThe top organic layer was collected
  4. customthe residual dimethylamine evaporated

Sources & evidence

ORD record
ord-abddae9c35c94ac3948e4cc72875c5ba
Source dataset
uspto-grants-1997_10
Patent number
US05679633

Reaction notes

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