3-Pyridinecarboxaldehyde → HCID 70338555, compound

Participants

Reaction Steps

5.4 g of 3-formylpyridine and three drops of concentrated hydrochloric acid are added to a solution of 7.8 g of 1-amino-2,3-dihydro-2-oxo4-tert-butyl-1H-imidazole in 50 ml of ethanol. The reaction mixture is refluxed for 30 minutes with stirring and then cooled to room temperature, upon which the mixture starts to crystallize. To complete the crystal precipitation process, 100 ml of diethyl ether are added to the mixture. The crystallizate is filtered off with suction, triturated with acetonitrile, again filtered off with suction and then dried. This gives the title compound which melts at 255°-256°.

Provenance & Evidence