tert-Butyl methyl ether → Acetone cyclohexane

Participants

Reaction Steps

Initially introduce 83.2 g (1.0 mol) of (E)-1-amino-2,4-pentadiene (title compound from Example B.2.) in 250 ml of MTBE and add 0.1 g of 4-hydroxyanisole. Subsequently add dropwise 229.2 g (1.05 mol) of di-tert-butyl dicarbonate dissolved in 250 ml of MTBE at an internal temperature of 20°-30° C. After addition is complete stir at room temperature for 20 h. Concentrate reaction mixture and take up in 1 l of toluene. Add 103.0 g (1.05 mol) of maleic anhydride and stir at an internal temperature of 60° C. for 24 h. Filter off precipitate with suction, wash with toluene and dry to constant weight at 50° C.

Provenance & Evidence