3-(piperidin-4-yl)-1,6-naphthyridin-2(1H)-one → 4-chloro-9-(2,2-dimethylpropyl)-7-[2-oxo-2-[4-(2-oxo-1H-1,6-naphthyridin-3-yl)piperidin-1-yl]ethyl]-3,6,7,10-tetrahydropyrazolo[3,4-i][2]benzazepin-8-one
Reaction equation
[Cl:18][c:19]1[cH:20][c:21]2[c:22]([c:23]3[cH:24][n:25][nH:26][c:27]13)[CH2:28][N:29]([CH2:54][C:55]([CH3:56])([CH3:57])[CH3:58])[C:30](=[O:53])[CH:31]([CH2:33][C:34]([N:35]1[CH2:36][CH2:37][CH:38]([N:39]3[CH2:40][c:41]4[c:42]([cH:43][cH:44][cH:45][cH:46]4)[NH:47][C:48]3=[O:49])[CH2:50][CH2:51]1)=[O:52])[CH2:32]2.[NH:1]1[CH2:2][CH2:3][CH:4]([c:7]2[c:8](=[O:17])[nH:9][c:10]3[cH:11][cH:12][n:13][cH:14][c:15]3[cH:16]2)[CH2:5][CH2:6]1>>[N:1]1([C:34]([CH2:33][CH:31]2[C:30](=[O:53])[N:29]([CH2:54][C:55]([CH3:56])([CH3:57])[CH3:58])[CH2:28][c:22]3[c:21]([cH:20][c:19]([Cl:18])[c:27]4[c:23]3[cH:24][n:25][nH:26]4)[CH2:32]2)=[O:52])[CH2:2][CH2:3][CH:4]([c:7]2[c:8](=[O:17])[nH:9][c:10]3[cH:11][cH:12][n:13][cH:14][c:15]3[cH:16]2)[CH2:5][CH2:6]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-6452360a8e684e0c9583fd4e334635c6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…