1,8-Diazabicyclo(5.4.0)undec-7-ene → HCID 21480493, compound

Participants

Reaction Steps

To a mixture of the product from Step B (10.2 g, 25.9 mmol) and molecular sieves (10 g) in ethyl acetate (150 mL) was added DBU (1 mL). The mixture was stirred overnight at ambient temperature, poured into a sainted solution of sodium bicarbonate (150 mL), and the organic layer was separated, dried and evaporated to give an oil (8.89 g, 91%).

Provenance & Evidence