Ethanolamine → HCID 131720262, compound

HRID 1490116Notes

Reaction equation

HRID 1490116 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:14][CH2:13][CH2:12][CH:11]([CH2:15][CH2:16][NH:17][CH2:18][CH2:19][OH:20])[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].C(O[C:26]([N:28]1[CH2:34][CH2:33][CH2:32][CH:31]([CH2:35][CH2:36]OS(C)(=O)=O)[CH2:30][CH2:29]1)=[O:27])(C)(C)C.C(CN)O.C1CCCCC1.[C:52]([O:55][CH2:56]C)(=[O:54])C>>[C:1]([O:5][C:6]([N:8]1[CH2:14][CH2:13][CH2:12][CH:11]([CH2:15][CH2:16][N:17]([CH2:18][CH2:19][OH:20])[C:26]([NH:28][C:34]2[CH:33]=[CH:32][C:31]([CH2:30][CH2:29][C:52]([O:55][CH3:56])=[O:54])=[CH:35][CH:36]=2)=[O:27])[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

5

Reactant 4

HCID 700EthanolamineHCID 21867204Cyclohexane ethylacetateHCID 70075532HCID 70075532, compoundHCID 88136247HCID 88136247, compound

Product 1

HCID 131720262HCID 131720262, compound

Procedure

The N-[2-(1-tert.butyloxycarbonyl-1-aza-4-cycloheptyl)-ethyl]-ethanolamine used as amine component is obtained by reacting 1-tert.butyloxycarbonyl-4-[2-(methane-sulfonyloxy)-ethyl]-1-azacycloheptane with ethanolamine. Rf value: 0.27 (Silica gel; cyclohexane/ethyl acetate=3:7)

Workup

  1. customis obtained

Sources & evidence

ORD record
ord-23d20b45432f4f5b8e37b9e9d2858c52
Source dataset
uspto-grants-1997_10
Patent number
US05681841

Reaction notes

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