Nitric Acid → HCID 22072743, compound

Participants

Reaction Steps

To a solution of 200 g of 2-(2-acetamidoethyl)-4,4', 5,5'-tetramethoxydeoxybenzoin in 2000 ml of acetic acid was slowly added 60 ml of 70% nitric acid at 0° C. Immediately after the addition, the mixture was poured into water and extracted with methylene chloride. The extract was neutralized with a sodium hydrogencarbonate aqueous solution and washed with a saturated sodium chloride aqueous solution. The solvent was removed under reduced pressure, and the residue was recrystallized from ethanol to yield 196 g of the title compound.

Provenance & Evidence