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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1490426Generated: October 27, 2026

1,2,3,4-Tetrahydroquinoline → 8-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,4-tetrahydroquinoline

https://huagongshe.com/reaction/1490426

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2,3,4-TetrahydroquinolineHCID 69460—
ReagentBis(pinacolato)diboraneHCID 2733548—
Reagent4,4,5,5-Tetramethyl[1,3,2]dioxaborolaneHCID 2734768—
Reagent4,4'-Di-tert-butyl-2,2'-bipyridylHCID 4249187—
CatalystBis(1,5-cyclooctadiene)dimethoxydiiridiumHCID 76001521—
SolventTetrahydrofuranHCID 8028—
Product8-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,4-tetrahydroquinolineHCID 12995921840%

Reaction Conditions

Temperature80 °C

Provenance & Evidence

DOI10.1021/ja1006405
Source datasetBorylation dataset from Roche
ORD IDord-b9eb3bf656504d8fbfe1133fbbb2747f
Source noteBorylation dataset from Roche