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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1490468Generated: October 30, 2026

3-(Trifluoromethyl)pyrazole → 5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)-1H-pyrazole

https://huagongshe.com/reaction/1490468

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)pyrazoleHCID 1807034—
Reagent3,4,7,8-Tetramethyl-1,10-phenanthrolineHCID 74265—
ReagentBis(pinacolato)diboraneHCID 2733548—
CatalystBis(1,5-cyclooctadiene)dimethoxydiiridiumHCID 76001521—
SolventTetrahydrofuranHCID 8028—
Product5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)-1H-pyrazoleHCID 7221344859%

Reaction Conditions

Temperature80 °C

Provenance & Evidence

DOI10.1021/ja412563e
Source datasetBorylation dataset from Roche
ORD IDord-61d61543df294f7bab9782933450500a
Source noteBorylation dataset from Roche