HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1490493Generated: November 3, 2026
N,N,2-Trimethylaniline → HCID 90213347, compound
https://huagongshe.com/reaction/1490493
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | N,N,2-Trimethylaniline | HCID 11869 | — |
| Reagent | Pinacol | HCID 6425 | — |
| Reagent | Triethylamine | HCID 8471 | — |
| Reagent | Catecholborane | HCID 67506 | — |
| Catalyst | Tris(pentafluorophenyl)borane | HCID 582056 | — |
| Product | HCID 90213347 | HCID 90213347 | 55% |
Reaction Steps
Prepared from N,N,2-trimethylaniline (1d, 13.5 mg, 0.100 mmol, 1.00 equiv) and catBH (60.0 mg, 0.500 mmol, 5.00 equiv) under neat conditions according to GP 1. The title compound was purified by flash column chromatography using cyclohexane/EtOAc/Et3N (30/1/1) as eluent to afford 3d (14.3 mg, 55%) as a colorless liquid.
Provenance & Evidence
| DOI | 10.1002/anie.201611536 |
|---|
| Source dataset | Borylation dataset from Roche |
|---|
| ORD ID | ord-91e5509ddafe45b5b92b297dc8b3990d |
|---|
| Source note | Borylation dataset from Roche |
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