HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1490503Generated: October 31, 2026
1-(Triisopropylsilyl)indole → HCID 11395451, compound
https://huagongshe.com/reaction/1490503
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-(Triisopropylsilyl)indole | HCID 11459999 | — |
| Reagent | Pinacol | HCID 6425 | — |
| Reagent | Triethylamine | HCID 8471 | — |
| Reagent | Norbornadiene | HCID 8473 | — |
| Reagent | Catecholborane | HCID 67506 | — |
| Catalyst | Tris(pentafluorophenyl)borane | HCID 582056 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 11395451 | HCID 11395451 | 61% |
Reaction Steps
Prepared from N-(triisopropylsilyl)-1H-indole (4a, 27.4 mg, 0.100 mmol, 1.00 equiv), catBH (24.0 mg, 0.200 mmol, 2.00 equiv), norbornene (18.8 mg, 0.100 mmol, 1.00 equiv) and B(C6F5)3 (5.1 mg, 0.010 mmol, 0.10 equiv) according to GP 3. The title compound was purified by flash column chromatography using cyclohexane/EtOAc/Et3N (30/1/1) as eluent to afford 3j (24.4 mg, 61%) as a white solid.
Provenance & Evidence
| DOI | 10.1002/anie.201611536 |
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| Source dataset | Borylation dataset from Roche |
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| ORD ID | ord-15f394501a194234ab9754975d2d9bdd |
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| Source note | Borylation dataset from Roche |
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