HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1490505Generated: November 3, 2026
HCID 24754945, compound → HCID 54671452, compound
https://huagongshe.com/reaction/1490505
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 24754945 | HCID 24754945 | — |
| Reagent | Pinacol | HCID 6425 | — |
| Reagent | Triethylamine | HCID 8471 | — |
| Reagent | Catecholborane | HCID 67506 | — |
| Catalyst | Tris(pentafluorophenyl)borane | HCID 582056 | — |
| Solvent | Chlorobenzene | HCID 7964 | — |
| Product | HCID 54671452 | HCID 54671452 | 59% |
Reaction Steps
Prepared from 5-chloro-N-(triisopropylsilyl)-1H-indole (4e, 30.7 mg, 0.100 mmol, 1.00 equiv) and catBH (48.0 mg, 0.400 mmol, 4.00 equiv) in chlorobenzene according to GP 2. The title compound was purified by flash column chromatography using cyclohexane/EtOAc/Et3N (30/1/1) as eluent to afford 6e[S4] (25.5 mg, 59%) as a white foam.
Provenance & Evidence
| DOI | 10.1002/anie.201611536 |
|---|
| Source dataset | Borylation dataset from Roche |
|---|
| ORD ID | ord-53e329e21ef444c4ac0a77bc66bd8fcd |
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| Source note | Borylation dataset from Roche |
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