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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1490578Generated: October 31, 2026

Ethyl 5-chloroindole-2-carboxylate → Ethyl 5-chloro-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-2-carboxylate

https://huagongshe.com/reaction/1490578

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 5-chloroindole-2-carboxylateHCID 78518—
Reagent4,4,5,5-Tetramethyl[1,3,2]dioxaborolaneHCID 2734768—
Reagent4,4'-Di-tert-butyl-2,2'-bipyridylHCID 4249187—
CatalystBis(1,5-cyclooctadiene)dimethoxydiiridiumHCID 76001521—
SolventHexaneHCID 8058—
ProductEthyl 5-chloro-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-2-carboxylateHCID 2496059783%

Reaction Conditions

Temperature60 °C

Provenance & Evidence

DOI10.1021/ja0631652
Source datasetBorylation dataset from Roche
ORD IDord-970318500f0d417f974b01cd94c26ded
Source noteBorylation dataset from Roche