HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1490631Generated: October 30, 2026
3-Fluorobenzaldehyde → 5-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde
https://huagongshe.com/reaction/1490631
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Fluorobenzaldehyde | HCID 68009 | — |
| Reagent | Tert-Butylamine | HCID 6385 | — |
| Reagent | 8-Aminoquinoline | HCID 11359 | — |
| Reagent | Bis(pinacolato)diborane | HCID 2733548 | — |
| Reagent | 4,4,5,5-Tetramethyl[1,3,2]dioxaborolane | HCID 2734768 | — |
| Catalyst | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 5-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde | HCID 59420279 | 72% |
Provenance & Evidence
| DOI | 10.1021/jacs.5b11683 |
|---|
| Source dataset | Borylation dataset from Roche |
|---|
| ORD ID | ord-ef61eb2886f44b3a9fc54db8ff1f4ecd |
|---|
| Source note | Borylation dataset from Roche |
|---|
