HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1490648Generated: November 1, 2026
alpha,alpha,alpha,3-Tetrafluorotoluene → 2-[2-Fluoro-4-(trifluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
https://huagongshe.com/reaction/1490648
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | alpha,alpha,alpha,3-Tetrafluorotoluene | HCID 67867 | — |
| Reagent | Bis(pinacolato)diborane | HCID 2733548 | — |
| Reagent | 4,4'-Di-tert-butyl-2,2'-bipyridyl | HCID 4249187 | — |
| Catalyst | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-[2-Fluoro-4-(trifluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | HCID 17750248 | 98% |
Provenance & Evidence
| DOI | 10.1021/jacs.6b13346 |
|---|
| Source dataset | Borylation dataset from Roche |
|---|
| ORD ID | ord-92c9ac9c929a4fdea76f5f6859eefa66 |
|---|
| Source note | Borylation dataset from Roche |
|---|
