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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1490656Generated: October 30, 2026

alpha,alpha,alpha,3-Tetrafluorotoluene → 2-[2-Fluoro-4-(trifluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

https://huagongshe.com/reaction/1490656

Reaction equation

Participants

RoleNameHCIDCharge
Reactantalpha,alpha,alpha,3-TetrafluorotolueneHCID 67867—
ReagentBis(pinacolato)diboraneHCID 2733548—
Reagent4,4'-Di-tert-butyl-2,2'-bipyridylHCID 4249187—
CatalystBis(1,5-cyclooctadiene)dimethoxydiiridiumHCID 76001521—
SolventTetrahydrofuranHCID 8028—
Product2-[2-Fluoro-4-(trifluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneHCID 1775024899%

Reaction Conditions

Temperature50 °C

Provenance & Evidence

DOI10.1021/jacs.6b13346
Source datasetBorylation dataset from Roche
ORD IDord-f4214cc02b1b47a69b4eba8b79c8ae72
Source noteBorylation dataset from Roche