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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1490663Generated: November 1, 2026

Benzoic acid, 3-fluoro-, ethyl ester → Ethyl 3-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate

https://huagongshe.com/reaction/1490663

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoic acid, 3-fluoro-, ethyl esterHCID 67975—
ReagentBis(pinacolato)diboraneHCID 2733548—
CatalystBis(1,5-cyclooctadiene)dimethoxydiiridiumHCID 76001521—
SolventDiisopropylethylamineHCID 81531—
ProductEthyl 3-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoateHCID 2313423054%

Reaction Conditions

Temperature60 °C

Provenance & Evidence

DOI10.1021/jacs.6b13346
Source datasetBorylation dataset from Roche
ORD IDord-175d1f64c5b245dc8b49e0a99856559a
Source noteBorylation dataset from Roche