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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1490701Generated: October 29, 2026

Ethyl 3-hydroxybenzoate → Ethyl 3-hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate

https://huagongshe.com/reaction/1490701

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 3-hydroxybenzoateHCID 24522—
ReagentBis(pinacolato)diboraneHCID 2733548—
Reagent4,4,5,5-Tetramethyl[1,3,2]dioxaborolaneHCID 2734768—
Reagent4,4'-Di-tert-butyl-2,2'-bipyridylHCID 4249187—
CatalystBis(1,5-cyclooctadiene)dimethoxydiiridiumHCID 76001521—
SolventCyclohexaneHCID 8078—
ProductEthyl 3-hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoateHCID 13006690982%
ProductEthyl 3-hydroxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoateHCID 13158653118%

Reaction Conditions

Temperature80 °C

Provenance & Evidence

DOI10.1021/jacs.7b02232
Source datasetBorylation dataset from Roche
ORD IDord-243778d5f5a048b2bc156278d3a99182
Source noteBorylation dataset from Roche