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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1490710Generated: October 25, 2026

Ethyl 2-chlorobenzoate → Ethyl 2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate

https://huagongshe.com/reaction/1490710

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-chlorobenzoateHCID 81783—
ReagentBis(pinacolato)diboraneHCID 2733548—
ReagentPotassium tert-butoxideHCID 86639980—
Reagent8-([2,2'-bipyridin]-5-yl)quinolin-2(1H)-oneHCID 164681385—
CatalystBis(1,5-cyclooctadiene)dimethoxydiiridiumHCID 76001521—
SolventTetrahydrofuranHCID 8028—
ProductEthyl 2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoateHCID 2203244193%

Reaction Conditions

Temperature80 °C

Provenance & Evidence

DOI10.1021/jacs.7b04490
Source datasetBorylation dataset from Roche
ORD IDord-4e26c2c361d941fa9c4e936c7bbe5a06
Source noteBorylation dataset from Roche