HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1490714Generated: October 25, 2026
2-Trifluoromethoxy-benzoic acid ethyl ester → 4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-2-trifluoromethoxy-benzoic acid ethyl ester
https://huagongshe.com/reaction/1490714
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Trifluoromethoxy-benzoic acid ethyl ester | HCID 44784883 | — |
| Reagent | Bis(pinacolato)diborane | HCID 2733548 | — |
| Reagent | Potassium tert-butoxide | HCID 86639980 | — |
| Reagent | 8-([2,2'-bipyridin]-5-yl)quinolin-2(1H)-one | HCID 164681385 | — |
| Catalyst | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-2-trifluoromethoxy-benzoic acid ethyl ester | HCID 138985642 | 89% |
Provenance & Evidence
| DOI | 10.1021/jacs.7b04490 |
|---|
| Source dataset | Borylation dataset from Roche |
|---|
| ORD ID | ord-c19d6f692f684d14aba5b6396d47d7d1 |
|---|
| Source note | Borylation dataset from Roche |
|---|
