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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1490724Generated: October 30, 2026

Ethyl 2-pyridinecarboxylate → Ethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinate

https://huagongshe.com/reaction/1490724

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-pyridinecarboxylateHCID 17307—
ReagentBis(pinacolato)diboraneHCID 2733548—
ReagentPotassium tert-butoxideHCID 86639980—
Reagent8-([2,2'-bipyridin]-5-yl)quinolin-2(1H)-oneHCID 164681385—
CatalystBis(1,5-cyclooctadiene)dimethoxydiiridiumHCID 76001521—
SolventTetrahydrofuranHCID 8028—
ProductEthyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinateHCID 997071077%

Reaction Conditions

Temperature80 °C

Provenance & Evidence

DOI10.1021/jacs.7b04490
Source datasetBorylation dataset from Roche
ORD IDord-a59bcab4b64c4ea8994eeb2cfcc415f2
Source noteBorylation dataset from Roche