HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1490730Generated: October 30, 2026
Benzoic acid, 3-fluoro-, ethyl ester → Ethyl 3-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate
https://huagongshe.com/reaction/1490730
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzoic acid, 3-fluoro-, ethyl ester | HCID 67975 | — |
| Reagent | Bis(pinacolato)diborane | HCID 2733548 | — |
| Reagent | Potassium tert-butoxide | HCID 86639980 | — |
| Reagent | 8-([2,2'-bipyridin]-5-yl)quinolin-2(1H)-one | HCID 164681385 | — |
| Catalyst | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | Ethyl 3-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate | HCID 23134230 | 69% |
Provenance & Evidence
| DOI | 10.1021/jacs.7b04490 |
|---|
| Source dataset | Borylation dataset from Roche |
|---|
| ORD ID | ord-21fd5ad70f2b45d7b267a6d6d00e149c |
|---|
| Source note | Borylation dataset from Roche |
|---|
