HCID 178523285, compound → HCID 178431091, compound

Participants

Reaction Conditions

Reaction Steps

Following general procedure F using 2,2,2‐trifluoro‐N‐(3‐(pyridin‐2‐yl)propyl)acetamide (58.1 mg, 0.25 mmol), B2pin2 (127 mg, 0.50 mmol), [Ir(COD)OMe]2 (2.5 mg, 0.00375 mmol) and dtbpy (2.0 mg, 0.0075 mmol) in THF (1.25 mL). The reaction was stirred at rt for 22 hours before cooling and the solvents removed. Analysis of crude 1 H NMR using internal standard 1,2‐dimethoxyethane showed 2.3:1 meta:para borylation in 70% yield. The crude product was unable to be purified by silica gel chromatography and was hence characterised from the crude mixture.    By subtracting

Provenance & Evidence