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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1490839Generated: October 29, 2026

Benzamide, N,N-dihexyl-2-trifluoromethyl- → N,N-dihexyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)benzamide

https://huagongshe.com/reaction/1490839

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzamide, N,N-dihexyl-2-trifluoromethyl-HCID 533223—
ReagentBis(pinacolato)diboraneHCID 2733548—
ReagentHCID 91820779HCID 91820779—
CatalystBis(1,5-cyclooctadiene)dimethoxydiiridiumHCID 76001521—
SolventP-XyleneHCID 7809—
ProductN,N-dihexyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)benzamideHCID 9182076296%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/nchem.2322
Source datasetBorylation dataset from Roche
ORD IDord-29ed77fe0ab64fc4bc2210d6ed3a253f
Source noteBorylation dataset from Roche