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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1490853Generated: October 30, 2026

(2-Bromophenyl)(morpholino)methanone → (2-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)(morpholino)methanone

https://huagongshe.com/reaction/1490853

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Bromophenyl)(morpholino)methanoneHCID 532184—
ReagentBis(pinacolato)diboraneHCID 2733548—
ReagentHCID 91820779HCID 91820779—
CatalystBis(1,5-cyclooctadiene)dimethoxydiiridiumHCID 76001521—
SolventP-XyleneHCID 7809—
Product(2-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)(morpholino)methanoneHCID 9182075673%
Product[2-Bromo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-morpholin-4-ylmethanoneHCID 14084735022%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/nchem.2322
Source datasetBorylation dataset from Roche
ORD IDord-5de16a0a2347498fb782c40075a5c6b9
Source noteBorylation dataset from Roche