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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1490854Generated: November 1, 2026

(2-Bromophenyl)(morpholino)methanone → [2-Bromo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-morpholin-4-ylmethanone

https://huagongshe.com/reaction/1490854

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Bromophenyl)(morpholino)methanoneHCID 532184—
ReagentBis(pinacolato)diboraneHCID 2733548—
Reagent4,4'-Di-tert-butyl-2,2'-bipyridylHCID 4249187—
CatalystBis(1,5-cyclooctadiene)dimethoxydiiridiumHCID 76001521—
SolventP-XyleneHCID 7809—
Product(2-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)(morpholino)methanoneHCID 918207562%
Product[2-Bromo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-morpholin-4-ylmethanoneHCID 1408473503%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/nchem.2322
Source datasetBorylation dataset from Roche
ORD IDord-4bb66224fa594d78924604a0f64cd160
Source noteBorylation dataset from Roche