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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1490882Generated: October 30, 2026

Ethyl 2-pyridinecarboxylate → Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carboxylate

https://huagongshe.com/reaction/1490882

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-pyridinecarboxylateHCID 17307—
ReagentBis(pinacolato)diboraneHCID 2733548—
Reagent4,4'-Di-tert-butyl-2,2'-bipyridylHCID 4249187—
CatalystBis(1,5-cyclooctadiene)dimethoxydiiridiumHCID 76001521—
SolventP-XyleneHCID 7809—
ProductEthyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinateHCID 997071040%
ProductEthyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carboxylateHCID 1177824252%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/nchem.2322
Source datasetBorylation dataset from Roche
ORD IDord-9766272943364fd583084c619b1b8e66
Source noteBorylation dataset from Roche