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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1490884Generated: October 30, 2026

Ethyl 2-pyridylacetate → Ethyl 2-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)acetate

https://huagongshe.com/reaction/1490884

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-pyridylacetateHCID 75960—
ReagentBis(pinacolato)diboraneHCID 2733548—
Reagent4,4'-Di-tert-butyl-2,2'-bipyridylHCID 4249187—
CatalystBis(1,5-cyclooctadiene)dimethoxydiiridiumHCID 76001521—
SolventP-XyleneHCID 7809—
ProductEthyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)acetateHCID 9182077729%
ProductEthyl 2-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)acetateHCID 13011587160%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/nchem.2322
Source datasetBorylation dataset from Roche
ORD IDord-a29ac6bd9d1f49e69747e6f4dc428766
Source noteBorylation dataset from Roche