HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Boc-pyrrolidine → tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrolidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Boc-pyrrolidine | HCID 643455 | — |
| Reagent | Bis(pinacolato)diborane | HCID 2733548 | — |
| Reagent | 2-Methyl-1,10-phenanthroline | HCID 4913356 | — |
| Catalyst | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Solvent | Cyclooctane | HCID 9266 | — |
| Product | tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrolidine-1-carboxylate | HCID 45787288 | 62% |
Reaction Conditions
| Temperature | 100 °C |
|---|
Provenance & Evidence
| DOI | 10.1126/science.aba6146 |
|---|---|
| Source dataset | Borylation dataset from Roche |
| ORD ID | ord-959f5f3d71fa48c38f9d040eb7f655dc |
| Source note | Borylation dataset from Roche |