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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491028Generated: October 30, 2026

4-[(E)-2-(4-Chlorophenyl)ethenyl]-6-methoxy-8-quinolinamine → HCID 178445216, compound

https://huagongshe.com/reaction/1491028

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[(E)-2-(4-Chlorophenyl)ethenyl]-6-methoxy-8-quinolinamineHCID 252521—
Reagent2,6-LutidineHCID 7937—
ReagentBis(pinacolato)diboraneHCID 2733548—
Reagent(11bR)-4-[[(1R)-2'-[[Tris(1-methylethyl)silyl]oxy][1,1'-binaphthalen]-2-yl]oxy]dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepinHCID 154720182—
Reagent1-Cyclohexyl-3-(2-pyridin-3-ylphenyl)ureaHCID 155936026—
CatalystBis(1,5-cyclooctadiene)dimethoxydiiridiumHCID 76001521—
SolventTolueneHCID 1140—
SolventCyclopentyl methyl etherHCID 138539—
ProductHCID 178445216HCID 17844521689%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1126/science.abc8320
Source datasetBorylation dataset from Roche
ORD IDord-622ce8d7ce4b4ae4b28c4ad6faabd029
Source noteBorylation dataset from Roche