HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491055Generated: October 31, 2026
N,3-dimethylbenzamide → N,5-dimethyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide
https://huagongshe.com/reaction/1491055
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | N,3-dimethylbenzamide | HCID 966002 | — |
| Reagent | Bis(pinacolato)diborane | HCID 2733548 | — |
| Reagent | HCID 178433626 | HCID 178433626 | — |
| Catalyst | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | N,5-dimethyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide | HCID 133668341 | 45% |
Reaction Steps
Isolated by chromatography using deactivated silica gel and ethyl acetate and petroleum ether (10:1 to 1:1) as the eluent.
Provenance & Evidence
| DOI | 10.1002/anie.201907366 |
|---|
| Source dataset | Borylation dataset from Roche |
|---|
| ORD ID | ord-b15e03684040477e867fb0e7118ab17a |
|---|
| Source note | Borylation dataset from Roche |
|---|
