HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491133Generated: October 25, 2026
1-Methoxy-4-(methylthio)benzene → 2-(2-Methoxy-5-methylsulfanylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
https://huagongshe.com/reaction/1491133
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-Methoxy-4-(methylthio)benzene | HCID 15885 | — |
| Reagent | 4,4'-Dimethyl-2,2'-bipyridine | HCID 14338 | — |
| Reagent | Bis(pinacolato)diborane | HCID 2733548 | — |
| Catalyst | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Solvent | P-Xylene | HCID 7809 | — |
| Product | 2-(2-Methoxy-5-methylsulfanylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | HCID 131515522 | 32% |
| Product | 2-(5-Methoxy-2-methylsulfanylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | HCID 132510260 | 31% |
Reaction Steps
dtbpy: A mixture of ortho- and meta-borylated products (88 mg, 63% yield, ortho/meta + para = 1.0); yellow solid;
Provenance & Evidence
| DOI | 10.1002/anie.201610041 |
|---|
| Source dataset | Borylation dataset from Roche |
|---|
| ORD ID | ord-c647f1265df44679848754ba33bea1e4 |
|---|
| Source note | Borylation dataset from Roche |
|---|
