HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491139Generated: October 25, 2026
4-Bromothioanisole → 2-(5-Bromo-2-methylsulfanylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
https://huagongshe.com/reaction/1491139
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Bromothioanisole | HCID 66037 | — |
| Reagent | 4,4'-Dimethyl-2,2'-bipyridine | HCID 14338 | — |
| Reagent | Bis(pinacolato)diborane | HCID 2733548 | — |
| Catalyst | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Solvent | P-Xylene | HCID 7809 | — |
| Product | 2-(5-Bromo-2-methylsulfanylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | HCID 132510261 | 57% |
| Product | HCID 178503104 | HCID 178503104 | 19% |
Reaction Steps
dtbpy: A mixture of ortho- and meta-borylated products (125 mg, 76% yield, ortho/meta + para = 3.0); yellow oil;
Provenance & Evidence
| DOI | 10.1002/anie.201610041 |
|---|
| Source dataset | Borylation dataset from Roche |
|---|
| ORD ID | ord-599a909af57c4391868aa64e3ee286a1 |
|---|
| Source note | Borylation dataset from Roche |
|---|
