化工社化工社 化学情報印刷レポート · 研究参考用
HRID 1491142作成日：2026年10月25日
N,N-Dimethyl-3-(methylsulfanyl)aniline → N,N-dimethyl-3-methylsulfanyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
https://huagongshe.com/reaction/1491142
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | N,N-Dimethyl-3-(methylsulfanyl)aniline | HCID 20403482 | — |
| 試薬 | Bis(pinacolato)diborane | HCID 2733548 | — |
| 試薬 | 2-Pyridin-2-yl-5-[2-[4-(trifluoromethyl)-1,3,2-dioxaborolan-2-yl]phenyl]pyridine | HCID 134956623 | — |
| 触媒 | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| 溶媒 | P-Xylene | HCID 7809 | — |
| 生成物 | N,N-dimethyl-3-methylsulfanyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline | HCID 132510266 | 76% |
反応手順
Ligand 3f: A mixture of ortho- and meta-borylated products (111 mg, 76% yield, ortho/meta + para = >30); ortho-borylated product 4h was obtained by further purification by GPC (100 mg, 68% yield), yellow oil;
情報源と証拠
| DOI | 10.1002/anie.201610041 |
|---|
| 出典データセット | Borylation dataset from Roche |
|---|
| ORD ID | ord-1cb889e2f933486bac022f3a0a595351 |
|---|
| 出典メモ | Borylation dataset from Roche |
|---|
