HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491144Generated: October 25, 2026
3-Methoxythioanisole → 2-(4-Methoxy-2-(methylthio)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
https://huagongshe.com/reaction/1491144
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Methoxythioanisole | HCID 281182 | — |
| Reagent | Bis(pinacolato)diborane | HCID 2733548 | — |
| Reagent | 2-Pyridin-2-yl-5-[2-[4-(trifluoromethyl)-1,3,2-dioxaborolan-2-yl]phenyl]pyridine | HCID 134956623 | — |
| Catalyst | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Solvent | P-Xylene | HCID 7809 | — |
| Product | 2-(4-Methoxy-2-(methylthio)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | HCID 138983102 | 60% |
Reaction Steps
Ligand 3f: A mixture of ortho- and meta-borylated products (84 mg, 60% yield, ortho/meta + para = >30); ortho-borylated product 4i was obtained by further purification by GPC (71 mg, 51% yield), colorless oil;
Provenance & Evidence
| DOI | 10.1002/anie.201610041 |
|---|
| Source dataset | Borylation dataset from Roche |
|---|
| ORD ID | ord-7487af86acf14633b8eaaa84b7fb2b65 |
|---|
| Source note | Borylation dataset from Roche |
|---|
