HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491150Generated: October 31, 2026
HCID 21355295, compound → HCID 177610935, compound
https://huagongshe.com/reaction/1491150
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 21355295 | HCID 21355295 | — |
| Reagent | Bis(pinacolato)diborane | HCID 2733548 | — |
| Reagent | 2-Pyridin-2-yl-5-[2-[4-(trifluoromethyl)-1,3,2-dioxaborolan-2-yl]phenyl]pyridine | HCID 134956623 | — |
| Catalyst | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Solvent | P-Xylene | HCID 7809 | — |
| Product | HCID 177610935 | HCID 177610935 | 62% |
Reaction Steps
Ligand 3f: A mixture of ortho- and meta-borylated products (91 mg, 62% yield, ortho/meta + para = >30); ortho-borylated product 4l was obtained by further purification by GPC (80 mg, 54% yield), colorless oil;
Provenance & Evidence
| DOI | 10.1002/anie.201610041 |
|---|
| Source dataset | Borylation dataset from Roche |
|---|
| ORD ID | ord-12ec8b3ea5864f8da66ba4813f640c50 |
|---|
| Source note | Borylation dataset from Roche |
|---|
