HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491152Generated: October 31, 2026
HCID 12498845, compound → HCID 132510267, compound
https://huagongshe.com/reaction/1491152
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 12498845 | HCID 12498845 | — |
| Reagent | Bis(pinacolato)diborane | HCID 2733548 | — |
| Reagent | 2-Pyridin-2-yl-5-[2-[4-(trifluoromethyl)-1,3,2-dioxaborolan-2-yl]phenyl]pyridine | HCID 134956623 | — |
| Catalyst | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Solvent | P-Xylene | HCID 7809 | — |
| Product | HCID 132510267 | HCID 132510267 | 83% |
Reaction Steps
Ligand 3f: A mixture of ortho- and meta-borylated products (134 mg, 83% yield, ortho/meta + para = >30); ortho-borylated product 4m was obtained by further purification by GPC (120 mg, 74% yield), yellow solid (mp. 98-100 oC);
Provenance & Evidence
| DOI | 10.1002/anie.201610041 |
|---|
| Source dataset | Borylation dataset from Roche |
|---|
| ORD ID | ord-256ae61c79424905b39cf35483e9f948 |
|---|
| Source note | Borylation dataset from Roche |
|---|
