HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491154Generated: November 4, 2026
1-Chloro-3-(methylthio)benzene → HCID 138982779, compound
https://huagongshe.com/reaction/1491154
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-Chloro-3-(methylthio)benzene | HCID 97585 | — |
| Reagent | Bis(pinacolato)diborane | HCID 2733548 | — |
| Reagent | 2-Pyridin-2-yl-5-[2-[4-(trifluoromethyl)-1,3,2-dioxaborolan-2-yl]phenyl]pyridine | HCID 134956623 | — |
| Catalyst | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Solvent | P-Xylene | HCID 7809 | — |
| Product | 2-[3-Chloro-5-(methylsulfanyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | HCID 53217245 | 10% |
| Product | HCID 138982779 | HCID 138982779 | 54% |
Reaction Steps
Ligand 3f: A mixture of ortho- and meta-borylated products (91 mg, 64% yield, ortho/meta + para = 5.1); ortho-borylated product 4n was obtained by further purification by GPC (60 mg, 42% yield), colorless oil;
Provenance & Evidence
| DOI | 10.1002/anie.201610041 |
|---|
| Source dataset | Borylation dataset from Roche |
|---|
| ORD ID | ord-6861f89fef964ee69d79922c8ba7d19d |
|---|
| Source note | Borylation dataset from Roche |
|---|
