HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491156Generated: November 1, 2026
3-Bromothioanisole → HCID 138982948, compound
https://huagongshe.com/reaction/1491156
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Bromothioanisole | HCID 2735627 | — |
| Reagent | Bis(pinacolato)diborane | HCID 2733548 | — |
| Reagent | 2-Pyridin-2-yl-5-[2-[4-(trifluoromethyl)-1,3,2-dioxaborolan-2-yl]phenyl]pyridine | HCID 134956623 | — |
| Catalyst | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Solvent | P-Xylene | HCID 7809 | — |
| Product | 2-[3-Bromo-5-(methylsulfanyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | HCID 53217130 | 10% |
| Product | HCID 138982948 | HCID 138982948 | 69% |
Reaction Steps
Ligand 3f: A mixture of ortho- and meta-borylated products (130 mg, 79% yield, ortho/meta + para = 6.7); ortho-borylated product 4o was obtained by further purification by GPC (96 mg, 59% yield), colorless oil;
Provenance & Evidence
| DOI | 10.1002/anie.201610041 |
|---|
| Source dataset | Borylation dataset from Roche |
|---|
| ORD ID | ord-e20e8efc8090420da8fb44189d3d0c23 |
|---|
| Source note | Borylation dataset from Roche |
|---|
