HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1491160Generated: October 31, 2026
HCID 85587722, compound → HCID 138983104, compound
https://huagongshe.com/reaction/1491160
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 85587722 | HCID 85587722 | — |
| Reagent | Bis(pinacolato)diborane | HCID 2733548 | — |
| Reagent | 2-Pyridin-2-yl-5-[2-[4-(trifluoromethyl)-1,3,2-dioxaborolan-2-yl]phenyl]pyridine | HCID 134956623 | — |
| Catalyst | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| Solvent | P-Xylene | HCID 7809 | — |
| Product | HCID 138983104 | HCID 138983104 | 77% |
Reaction Steps
Ligand 3f: A mixture of ortho- and meta-borylated products (124 mg, 77% yield, ortho/meta + para = >30); ortho-borylated product 4q was obtained by further purification by GPC (91 mg, 57% yield), yellow solid (mp. 118-120 oC)
Provenance & Evidence
| DOI | 10.1002/anie.201610041 |
|---|
| Source dataset | Borylation dataset from Roche |
|---|
| ORD ID | ord-261363779ac04db78063622240d8f3f6 |
|---|
| Source note | Borylation dataset from Roche |
|---|
